The present study aimed that evaluation anti hyperlipidemic activity of root and leaf of the Bauhinia rufescens Lam, leaves of Cassia auriculata L, leaves and flowers of Mimosa pudica L by Maceration method. Individually and combined plants extracted poly herbal extraction and screened for phytochemical study performed Preliminary Phytochemical analysis of crude extracts for root and leaf of the Bauhinia rufescens Lam, leaves of Cassia auriculata L, leaves and flowers of Mimosa pudica L and poly herbal extraction for Anti-Hyperlipidemic activity by Triton X 100 Induced Hyperlipidemia model, High Fat Diet (FD) induced hyperlipidemic model, Estimation of Serum total cholesterol (TC) CHOD- PAP, Estimation of serum triglycerides, Estimation of HDL-cholesterol, Estimation of LDL cholesterol, Phytochemical investigation reveals the presence of alkaloids, flavanoids, saponins, tannins, steroids, triterpenoids, carbohydrates and glycosides in poly herbal methanolic extraction and individual plant extraction, In acute toxicity studies no mortality was observed with either of the extracts even at the dose level of 2000mg/kg body weight. In the present study, the methanol extracts of three plants reduced the cholesterol and triglycerides in a manner similar to the reduction facilitated by atorvastatin. The hypolipidemic activities of atorvastatin and the methanol extract of individual and polyherbal extraction were evident in both synthesis and excretory phases of triton-induced hyperlipidemia in rats. Keywords: Bauhinia rufescens Lam, Cassia auriculata L, Mimosa pudica L.
