1. | PANDEMIC VIEW OF QUADRUPLE REASSORTMENT VIRUS-(SARS-CoV2) |
| S. Swarnalatha*, A.Ashwathi, T. Aarthi, S.Bhuvaneshwari, B. Divyakala,S. Bhuvaneshwari |
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Article Type:Research Article/
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No of Download=394 |
Pages (1-5) |
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The Covid 19 became the most dread full disease of this 20th century shaking the whole world and still fights for the precise cure apart from natural immunological response. Shifting from epidemic to pandemic nature of this virus within a short duration exhibits the severe nature of its threat to the man kind. Animal viruses have their genetic material copied by the host cell after which they are released into the environment to cause disease. Animal viruses mainly infects animal cells and causes different diseases in animals including humans. Some animal viruses are so deadliest in this world. COVID-19 is a disease caused by one of the deadliest viruses called (Severe Acute Respiratory Syndrome Corona Virus 2) SARS-CoV2. It is a positive sense single-stranded RNA virus causing respiratory illness. This strain was first discovered in Wuhan, China and so called as Wuhan virus. In this review article, we discussed about the general overview of COVID-19 including their mutations, transmissibility, clinical manifestations, diagnosis, and treatment.
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2. | EVALUATION OF NOOTROPIC AND ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF CROSSANDRA INFUNDIBULIFORMIS |
| G.Muthukumaran*, Prasanth.A, V.Suresh, G.Thamotharan, N. Senthil Kumar, D.C.Premanand, R.Kannan, Deepan. N |
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Article Type:Research Article/
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No of Download=426 |
Pages (6-11) |
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To evaluate the Nootropic and Anticonvulsant activity of the ethanolic extract of the leaves of crossandra infundibuliformis. Nootropic activity was evaluated by scopolamine induced dementia animal model with elevated plus maze and object identification procedures were done. The Inflexion ratio [IR] specific for continue memory and Discrimination intex [DI], specific for selective memory were evaluated respectively from the above test. and the Anticonvulsant activity was evaluated on an adult wister rats. Two different study models such as, Maximal electroshock [MES] and Isoniazid [INH] induced convulsion method. Nootropic and Anticonvulsant activity were performed in two different concentration such as 200mg/kg, 400mg/kg of EECI. Both the activities were dose dependent. The largest concentration showed the maximum activity.The present study concluded that the ethanolic extract of Crossandra infundibuliformis possessed Nootropic and Anticonvulsant Action. Nootropic and Anticonvulsant activity leads some support to the use of Crossandra infundibuliformis for different disease in the folkloric medicine of india.
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